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Macrophage-Tropic Simian/Human Immunodeficiency Virus Chimeras Use CXCR4, Not CCR5, for Infections of Rhesus Macaque Peripheral Blood Mononuclear Cells and Alveolar Macrophages

After the nearly complete and irreversible depletion of CD4(+) T lymphocytes induced by highly pathogenic simian/human immunodeficiency virus chimeric viruses (SHIVs) during infections of rhesus monkeys, tissue macrophages are able to sustain high levels (>10(6) viral RNA copies/ml) of plasma viremi...

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Vydáno v:J Virol
Hlavní autoři: Igarashi, Tatsuhiko, Donau, Olivia K., Imamichi, Hiromi, Dumaurier, Marie-Jeanne, Sadjadpour, Reza, Plishka, Ronald J., Buckler-White, Alicia, Buckler, Charles, Suffredini, Anthony F., Lane, H. Clifford, Moore, John P., Martin, Malcolm A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296065/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14645561/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.24.13042-13052.2003
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