Emergence of a highly pathogenic simian/human immunodeficiency virus in a rhesus macaque treated with anti-CD8 mAb during a primary infection with a nonpathogenic virus

Although simian/human immunodeficiency virus (SHIV) strain DH12 replicates to high titers and causes immunodeficiency in pig-tailed macaques, virus loads measured in SHIV(DH12)-infected rhesus monkeys are consistently 100-fold lower and none of 22 inoculated animals have developed disease. We previo...

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Detalhes bibliográficos
Main Authors: Igarashi, Tatsuhiko, Endo, Yasuyuki, Englund, George, Sadjadpour, Reza, Matano, Tetsuro, Buckler, Charles, Buckler-White, Alicia, Plishka, Ron, Theodore, Ted, Shibata, Riri, Martin, Malcolm
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1999
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC24188/
https://ncbi.nlm.nih.gov/pubmed/10570196
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