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Signals That Dictate Nuclear Localization of Human Papillomavirus Type 16 Oncoprotein E6 in Living Cells

Human papillomavirus (HPV) type 16 E6 (16E6) is an oncogenic, multifunctional nuclear protein that induces p53 degradation and perturbs normal cell cycle control, leading to immortalization and transformation of infected keratinocytes and epithelial cells. Although it is unclear how 16E6 disrupts th...

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Detalhes bibliográficos
Main Authors: Tao, Mingfang, Kruhlak, Michael, Xia, Shuhua, Androphy, Elliot, Zheng, Zhi-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC296047/
https://ncbi.nlm.nih.gov/pubmed/14645580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.24.13232-13247.2003
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