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Improved Coreceptor Usage Prediction and Genotypic Monitoring of R5-to-X4 Transition by Motif Analysis of Human Immunodeficiency Virus Type 1 env V3 Loop Sequences

Early in infection, human immunodeficiency virus type 1 (HIV-1) generally uses the CCR5 chemokine receptor (along with CD4) for cellular entry. In many HIV-1-infected individuals, viral genotypic changes arise that allow the virus to use CXCR4 (either in addition to CCR5 or alone) as an entry corece...

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Vydáno v:J Virol
Hlavní autoři: Jensen, Mark A., Li, Fu-Sheng, van ’t Wout, Angélique B., Nickle, David C., Shriner, Daniel, He, Hong-Xia, McLaughlin, Sherry, Shankarappa, Raj, Margolick, Joseph B., Mullins, James I.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2003
Témata:
Recombination and Evolution
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296044/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14645592/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.24.13376-13388.2003
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