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High levels of p19/nm23 protein in neuroblastoma are associated with advanced stage disease and with N-myc gene amplification.

The gene encoding a novel protein designated nm23-H1, which was recently identified as identical to the A subunit of nucleotide diphosphate kinase from human erythrocytes, has been proposed to play a role in tumor metastasis suppression. We report that untreated neuroblastoma tumors contain a cellul...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Hailat, N, Keim, D R, Melhem, R F, Zhu, X X, Eckerskorn, C, Brodeur, G M, Reynolds, C P, Seeger, R C, Lottspeich, F, Strahler, J R
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1991
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296039/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2056128/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115299
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