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Reduction in susceptibility to natural killer cell-mediated lysis of human FO-1 melanoma cells after induction of HLA class I antigen expression by transfection with B2m gene.

Induction of HLA class I antigens on cultured melanoma cells FO-1 after transfection with a human or a mouse B2m gene was associated with a statistically significant reduction in their susceptibility to natural killer (NK) cell-mediated lysis. These results indicate that the structural differences b...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Maio, M, Altomonte, M, Tatake, R, Zeff, R A, Ferrone, S
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1991
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296030/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1905328/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115289
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