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Hormone-mediated down-regulation of hepatic glutathione synthesis in the rat.
Our present work characterized the role of hormone-mediated signal transduction pathways in regulating hepatic reduced glutathione (GSH) synthesis. Cholera toxin, dibutyryl cAMP (DBcAMP), and glucagon inhibited GSH synthesis in cultured hepatocytes by 25-43%. Cellular cAMP levels exhibited a lower t...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296028/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1647417/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115286 |
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