Hormone-mediated down-regulation of hepatic glutathione synthesis in the rat.

Our present work characterized the role of hormone-mediated signal transduction pathways in regulating hepatic reduced glutathione (GSH) synthesis. Cholera toxin, dibutyryl cAMP (DBcAMP), and glucagon inhibited GSH synthesis in cultured hepatocytes by 25-43%. Cellular cAMP levels exhibited a lower t...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Lu, S C, Kuhlenkamp, J, Garcia-Ruiz, C, Kaplowitz, N
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1991
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296028/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1647417/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115286
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