Transfer of 15-lipoxygenase gene into rabbit iliac arteries results in the appearance of oxidation-specific lipid-protein adducts characteristic of oxidized low density lipoprotein.

Oxidized low density lipoprotein (LDL) possesses several atherogenic properties. The mechanisms by which LDL becomes oxidized in vivo remain unknown, but previous studies have suggested that 15-lipoxygenase may be one of the factors involved in the initiation of LDL oxidation in the arterial wall. 3...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Ylä-Herttuala, S, Luoma, J, Viita, H, Hiltunen, T, Sisto, T, Nikkari, T
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1995
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295952/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7769108/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117971
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