Expression of two human skeletal calcitonin receptor isoforms cloned from a giant cell tumor of bone. The first intracellular domain modulates ligand binding and signal transduction.

Two distinct calcitonin (CT) receptor (CTR)-encoding cDNAs (designated GC-2 and GC-10) were cloned and characterized from giant cell tumor of bone (GCT). Both GC-2 and GC-10 differ structurally from the human ovarian cell CTR (o-hCTR) that we cloned previously, but differ from each other only by the...

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Detalhes bibliográficos
Main Authors: Gorn, A H, Rudolph, S M, Flannery, M R, Morton, C C, Weremowicz, S, Wang, T Z, Krane, S M, Goldring, S R
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC295951/
https://ncbi.nlm.nih.gov/pubmed/7769107
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