The intriguing Cyclophilin A-HIV-1 Vpr interaction: prolyl cis/trans isomerisation catalysis and specific binding

BACKGROUND: Cyclophilin A (CypA) represents a potential target for antiretroviral therapy since inhibition of CypA suppresses human immunodeficiency virus type 1 (HIV-1) replication, although the mechanism through which CypA modulates HIV-1 infectivity still remains unclear. The interaction of HIV-1...

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Hlavní autoři: Solbak, Sara M, Reksten, Tove R, Wray, Victor, Bruns, Karsten, Horvli, Ole, Raae, Arnt J, Henklein, Petra, Henklein, Peter, Röder, Rene, Mitzner, David, Schubert, Ulrich, Fossen , Torgils
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2959089/
https://ncbi.nlm.nih.gov/pubmed/20920334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-10-31
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