Proline 35 of Human Immunodeficiency Virus Type 1 (HIV-1) Vpr Regulates the Integrity of the N-Terminal Helix and the Incorporation of Vpr into Virus Particles and Supports the Replication of R5-Tropic HIV-1 in Human Lymphoid Tissue Ex Vivo

Mutational analysis of the four conserved proline residues in human immunodeficiency virus type 1 (HIV-1) Vpr reveals that only Pro-35 is required for efficient replication of R5-tropic, but not of X4-tropic, viruses in human lymphoid tissue (HLT) cultivated ex vivo. While Vpr-mediated apoptosis and...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Votteler, Jörg, Studtrucker, Nicole, Sörgel, Stefan, Münch, Jan, Rücker, Elke, Kirchhoff, Frank, Schick, Bernhard, Henklein, Peter, Fossen, Torgils, Bruns, Karsten, Sharma, Alok, Wray, Victor, Schubert, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951402/
https://ncbi.nlm.nih.gov/pubmed/17553868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02803-06
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados