GPI-anchored single chain Fv - an effective way to capture transiently-exposed neutralization epitopes on HIV-1 envelope spike

BACKGROUND: Identification of broad neutralization epitopes in HIV-1 envelope spikes is paramount for HIV-1 vaccine development. A few broad neutralization epitopes identified so far are present on the surface of native HIV-1 envelope spikes whose recognition by antibodies does not depend on conform...

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Détails bibliographiques
Auteurs principaux: Wen, Michael, Arora, Reetakshi, Wang, Huiqiang, Liu, Lihong, Kimata, Jason T, Zhou, Paul
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2959034/
https://ncbi.nlm.nih.gov/pubmed/20923574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-7-79
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