Differential regulation of p53 function by the N-terminal ΔNp53 and Δ113p53 isoforms in zebrafish embryos

BACKGROUND: The p53 protein family coordinates stress responses of cells and organisms. Alternative promoter usage and/or splicing of p53 mRNA gives rise to at least nine mammalian p53 proteins with distinct N- and C-termini which are differentially expressed in normal and malignant cells. The human...

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Main Authors: Davidson, William R, Kari, Csaba, Ren, Qing, Daroczi, Borbala, Dicker, Adam P, Rodeck, Ulrich
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958959/
https://ncbi.nlm.nih.gov/pubmed/20929554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-10-102
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