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Impacts of mutation effects and population size on mutation rate in asexual populations: a simulation study

BACKGROUND: In any natural population, mutation is the primary source of genetic variation required for evolutionary novelty and adaptation. Nevertheless, most mutations, especially those with phenotypic effects, are harmful and are consequently removed by natural selection. For this reason, under n...

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Main Authors: Jiang, Xiaoqian, Mu, Baolin, Huang, Zhuoran, Zhang, Mingjing, Wang, Xiaojuan, Tao, Shiheng
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958918/
https://ncbi.nlm.nih.gov/pubmed/20920286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-10-298
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