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The Influence of Deleterious Mutations on Adaptation in Asexual Populations

We study the dynamics of adaptation in asexual populations that undergo both beneficial and deleterious mutations. In particular, how the deleterious mutations affect the fixation of beneficial mutations was investigated. Using extensive Monte Carlo simulations, we find that in the “strong-selection...

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Main Authors: Jiang, Xiaoqian, Xu, Zhao, Li, Jingjing, Shi, Youyi, Wu, Wenwu, Tao, Shiheng
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215719/
https://ncbi.nlm.nih.gov/pubmed/22110756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027757
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