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TGFβ signaling in the brain increases with aging and signals to astrocytes and innate immune cells in the weeks after stroke

BACKGROUND: TGFβ is both neuroprotective and a key immune system modulator and is likely to be an important target for future stroke therapy. The precise function of increased TGF-β1 after stroke is unknown and its pleiotropic nature means that it may convey a neuroprotective signal, orchestrate gli...

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Autori principali: Doyle, Kristian P, Cekanaviciute, Egle, Mamer, Lauren E, Buckwalter, Marion S
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958905/
https://ncbi.nlm.nih.gov/pubmed/20937129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-7-62
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