Mycobacterium leprae Phenolglycolipid-1 Expressed by Engineered M. bovis BCG Modulates Early Interaction with Human Phagocytes

The species-specific phenolic glycolipid 1 (PGL-1) is suspected to play a critical role in the pathogenesis of leprosy, a chronic disease of the skin and peripheral nerves caused by Mycobacterium leprae. Based on studies using the purified compound, PGL-1 was proposed to mediate the tropism of M. le...

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Main Authors: Tabouret, Guillaume, Astarie-Dequeker, Catherine, Demangel, Caroline, Malaga, Wladimir, Constant, Patricia, Ray, Aurélie, Honoré, Nadine, Bello, Nana Fatimath, Perez, Esther, Daffé, Mamadou, Guilhot, Christophe
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958813/
https://ncbi.nlm.nih.gov/pubmed/20975946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001159
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