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Developmental Pharmacogenetics in Pediatric Rheumatology: Utilizing a New Paradigm to Effectively Treat Patients with Juvenile Idiopathic Arthritis with Methotrexate

Although methotrexate is widely used in clinical practice there remains significant lack of understanding of its mechanisms of action and the factors that contribute to the variability in toxicity and response seen clinically. In addition to differences in drug administration, factors that affect ph...

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Autors principals: Becker, Mara L., Leeder, J. Steven
Format: Artigo
Idioma:Inglês
Publicat: SAGE-Hindawi Access to Research 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958653/
https://ncbi.nlm.nih.gov/pubmed/20981233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/257120
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