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Developmental Pharmacogenetics in Pediatric Rheumatology: Utilizing a New Paradigm to Effectively Treat Patients with Juvenile Idiopathic Arthritis with Methotrexate

Although methotrexate is widely used in clinical practice there remains significant lack of understanding of its mechanisms of action and the factors that contribute to the variability in toxicity and response seen clinically. In addition to differences in drug administration, factors that affect ph...

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Autori principali: Becker, Mara L., Leeder, J. Steven
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE-Hindawi Access to Research 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958653/
https://ncbi.nlm.nih.gov/pubmed/20981233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/257120
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