Ankyrin G restricts ion channel diffusion at the axonal initial segment before the establishment of the diffusion barrier

In mammalian neurons, the precise accumulation of sodium channels at the axonal initial segment (AIS) ensures action potential initiation. This accumulation precedes the immobilization of membrane proteins and lipids by a diffusion barrier at the AIS. Using single-particle tracking, we measured the...

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Bibliographic Details
Main Authors: Brachet, Anna, Leterrier, Christophe, Irondelle, Marie, Fache, Marie-Pierre, Racine, Victor, Sibarita, Jean-Baptiste, Choquet, Daniel, Dargent, Bénédicte
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2010
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958486/
https://ncbi.nlm.nih.gov/pubmed/20956383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201003042
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