Protein kinase CK2 contributes to the organization of sodium channels in axonal membranes by regulating their interactions with ankyrin G

In neurons, generation and propagation of action potentials requires the precise accumulation of sodium channels at the axonal initial segment (AIS) and in the nodes of Ranvier through ankyrin G scaffolding. We found that the ankyrin-binding motif of Na(v)1.2 that determines channel concentration at...

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Detalhes bibliográficos
Main Authors: Bréchet, Aline, Fache, Marie-Pierre, Brachet, Anna, Ferracci, Géraldine, Baude, Agnés, Irondelle, Marie, Pereira, Sandrine, Leterrier, Christophe, Dargent, Bénédicte
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600743/
https://ncbi.nlm.nih.gov/pubmed/19064667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200805169
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