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A Genetic Model of Chronic Rhinosinusitis-Associated Olfactory Inflammation Reveals Reversible Functional Impairment and Dramatic Neuroepithelial Reorganization

Inflammatory sinus and nasal disease is a common cause of human olfactory loss. To explore the mechanisms underlying rhinosinusitis-associated olfactory loss, we have generated a transgenic mouse model of olfactory inflammation, in which tumor necrosis factor α (TNF-α) expression is induced in a tem...

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Hlavní autoři: Lane, Andrew P., Turner, Justin, May, Lindsey, Reed, Randall
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957830/
https://ncbi.nlm.nih.gov/pubmed/20147558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4507-09.2010
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