Defining a rat blood pressure quantitative trait locus to a <81.8 kb congenic segment: comprehensive sequencing and renal transcriptome analysis

Evidence from multiple linkage and genome-wide association studies suggest that human chromosome 2 (HSA2) contains alleles that influence blood pressure (BP). Homologous to a large segment of HSA2 is rat chromosome 9 (RNO9), to which a BP quantitative trait locus (QTL) was previously mapped. The obj...

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Main Authors: Gopalakrishnan, K., Saikumar, J., Peters, C. G., Kumarasamy, S., Farms, P., Yerga-Woolwine, S., Toland, E. J., Schnackel, W., Giovannucci, D. R., Joe, B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957796/
https://ncbi.nlm.nih.gov/pubmed/20716646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00122.2010
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