Effect of Recombinant Human Lecithin Cholesterol Acyltransferase Infusion on Lipoprotein Metabolism in Mice

Lecithin cholesterol acyl transferase (LCAT) deficiency is associated with low high-density lipoprotein (HDL) and the presence of an abnormal lipoprotein called lipoprotein X (Lp-X) that contributes to end-stage renal disease. We examined the possibility of using LCAT an as enzyme replacement therap...

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Bibliografiske detaljer
Main Authors: Rousset, Xavier, Vaisman, Boris, Auerbach, Bruce, Krause, Brian R., Homan, Reyn, Stonik, John, Csako, Gyorgy, Shamburek, Robert, Remaley, Alan T.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2010
Fag:
Cardiovascular
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957790/
https://ncbi.nlm.nih.gov/pubmed/20605907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.169540
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