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IKKβ inhibitor identification: a multi-filter driven novel scaffold
BACKGROUND: Nuclear factor kappa B (NF-κB) is a chief nuclear transcription factor that controls the transcription of various genes; and its activation is tightly controlled by Inhibitor kappa B kinase (IKK). The irregular transcription of NF-κB has been linked to auto-immune disorders, cancer and o...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2957683/ https://ncbi.nlm.nih.gov/pubmed/21106122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-S7-S15 |
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