Plasma C-Terminal Pro-Endothelin-1 Is Associated With Target-Organ Damage in African Americans With Hypertension

BACKGROUND: Endothelin-1 (ET-1) is a vasoactive peptide with vasoconstrictor and mitogenic properties. We investigated whether plasma levels of C-terminal pro-ET-1 (CT-proET-1), a newly described stable fragment of the ET-1 precursor, are associated with target-organ damage in hypertension. METHODS:...

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Hauptverfasser: Habib, Ammar, Al-Omari, Malik A., Khaleghi, Mahyar, Morgenthaler, Nils G., Struck, Joachim, Bergmann, Andreas, Mosley, Thomas H., Turner, Stephen T., Kullo, Iftikhar J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957561/
https://ncbi.nlm.nih.gov/pubmed/20634796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajh.2010.149
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