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Plasma C-Terminal Pro–Endothelin-1 is Associated with Left Ventricular Mass Index and Aortic Root Diameter in African American Adults with Hypertension

BACKGROUND: Endothelin-1 (ET-1), a circulating vasoactive peptide with a potent vasoconstricting and mitogenic properties, may contribute to target-organ damage in hypertension. A novel assay for the measurement of C-terminal pro-endothelin-1 (CT-proET-1), a stable fragment of ET-1 precursor, has be...

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Detalhes bibliográficos
Main Authors: Al-Omari, Malik A.M., Khaleghi, Mahyar, Mosley, Thomas H., Morgenthaler, Nils G., Struck, Joachim, Bergmann, Andreas, Kullo, Iftikhar J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921559/
https://ncbi.nlm.nih.gov/pubmed/20182452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jhh.2010.20
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