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Xanthine oxidase inhibits growth of Plasmodium falciparum in human erythrocytes in vitro.

Malaria parasites, unable to synthesize purine de novo, use host-derived hypoxanthine preferentially as purine source. In a previous study (1990. J. Biol. Chem. 265:6562-6568), we noted that xanthine oxidase rapidly and completely depleted hypoxanthine in human erythrocytes, not by crossing the eryt...

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Autors principals: Berman, P A, Human, L, Freese, J A
Format: Artigo
Idioma:Inglês
Publicat: 1991
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC295752/
https://ncbi.nlm.nih.gov/pubmed/1752946
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