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Xanthine oxidase inhibits growth of Plasmodium falciparum in human erythrocytes in vitro.
Malaria parasites, unable to synthesize purine de novo, use host-derived hypoxanthine preferentially as purine source. In a previous study (1990. J. Biol. Chem. 265:6562-6568), we noted that xanthine oxidase rapidly and completely depleted hypoxanthine in human erythrocytes, not by crossing the eryt...
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| Udgivet i: | J Clin Invest |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1991
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295752/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1752946/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115506 |
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