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Xanthine oxidase inhibits growth of Plasmodium falciparum in human erythrocytes in vitro.

Malaria parasites, unable to synthesize purine de novo, use host-derived hypoxanthine preferentially as purine source. In a previous study (1990. J. Biol. Chem. 265:6562-6568), we noted that xanthine oxidase rapidly and completely depleted hypoxanthine in human erythrocytes, not by crossing the eryt...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Berman, P A, Human, L, Freese, J A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 1991
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295752/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1752946/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115506
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