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Critical role for lactate dehydrogenase A in aerobic glycolysis that sustains pulmonary microvascular endothelial cell proliferation

Pulmonary microvascular endothelial cells possess both highly proliferative and angiogenic capacities, yet it is unclear how these cells sustain the metabolic requirements essential for such growth. Rapidly proliferating cells rely on aerobic glycolysis to sustain growth, which is characterized by g...

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Detalhes bibliográficos
Main Authors: Parra-Bonilla, Glenda, Alvarez, Diego F., Al-Mehdi, Abu-Bakr, Alexeyev, Mikhail, Stevens, Troy
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957419/
https://ncbi.nlm.nih.gov/pubmed/20675437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00274.2009
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