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Characterizing Tyrosine Phosphorylation Signaling in Lung Cancer Using SH2 Profiling

BACKGROUND: Tyrosine kinases drive the proliferation and survival of many human cancers. Thus profiling the global state of tyrosine phosphorylation of a tumor is likely to provide a wealth of information that can be used to classify tumors for prognosis and prediction. However, the comprehensive an...

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Autori principali: Machida, Kazuya, Eschrich, Steven, Li, Jiannong, Bai, Yun, Koomen, John, Mayer, Bruce J., Haura, Eric B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957407/
https://ncbi.nlm.nih.gov/pubmed/20976048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013470
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