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Phosphoproteomics Identifies Driver Tyrosine Kinases in Sarcoma Cell Lines and Tumors

Driver tyrosine kinase mutations are rare in sarcomas, and patterns of tyrosine phosphorylation are poorly understood. To better understand the signaling pathways active in sarcoma, we examined global tyrosine phosphorylation in sarcoma cell lines and human tumor samples. Anti-phosphotyrosine antibo...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Bai, Yun, Li, Jiannong, Fang, Bin, Edwards, Arthur, Zhang, Guolin, Bui, Marilyn, Eschrich, Steven, Altiok, Soner, Koomen, John, Haura, Eric B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641440/
https://ncbi.nlm.nih.gov/pubmed/22461510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3015
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