Phosphoproteomics Identifies Driver Tyrosine Kinases in Sarcoma Cell Lines and Tumors

Driver tyrosine kinase mutations are rare in sarcomas, and patterns of tyrosine phosphorylation are poorly understood. To better understand the signaling pathways active in sarcoma, we examined global tyrosine phosphorylation in sarcoma cell lines and human tumor samples. Anti-phosphotyrosine antibo...

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Bibliographic Details
Published in:Cancer Res
Main Authors: Bai, Yun, Li, Jiannong, Fang, Bin, Edwards, Arthur, Zhang, Guolin, Bui, Marilyn, Eschrich, Steven, Altiok, Soner, Koomen, John, Haura, Eric B.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641440/
https://ncbi.nlm.nih.gov/pubmed/22461510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3015
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