A Smac Mimetic Reduces TNF Related Apoptosis Inducing Ligand (TRAIL)-Induced Invasion and Metastasis of Cholangiocarcinoma Cells

Cholangiocarcinoma (CCA) cells paradoxically express tumor necrosis factor–related apoptosis-inducing ligand (TRAIL), a death ligand that, failing to kill CCA cells, instead promotes their tumorigenicity and especially the metastatic behaviors of cell migration and invasion. Second mitochondria-deri...

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Autors principals: Fingas, Christian D., Blechacz, Boris R. A., Smoot, Rory L., Guicciardi, Maria E., Mott, Justin, Bronk, Steve F., Werneburg, Nathan W., Sirica, Alphonse E., Gores, Gregory J.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957364/
https://ncbi.nlm.nih.gov/pubmed/20683954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23729
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