Aldehyde Dehydrogenase 1B1: Molecular Cloning and Characterization of a Novel Mitochondrial Acetaldehyde-Metabolizing Enzyme

Ethanol-induced damage is largely attributed to its toxic metabolite, acetaldehyde. Clearance of acetaldehyde is achieved by its oxidation, primarily catalyzed by the mitochondrial class II aldehyde dehydrogenase (ALDH2). ALDH1B1 is another mitochondrial aldehyde dehydrogenase (ALDH) that shares 75%...

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Bibliografski detalji
Glavni autori: Stagos, Dimitrios, Chen, Ying, Brocker, Chad, Donald, Elizabeth, Jackson, Brian C., Orlicky, David J., Thompson, David C., Vasiliou, Vasilis
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2010
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Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957164/
https://ncbi.nlm.nih.gov/pubmed/20616185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.110.034678
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