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Dead enzymes in the aldehyde dehydrogenase gene family: Role in drug metabolism and toxicology
INTRODUCTION: Dead enzymes are gene products (proteins) that lack key residues required for catalytic activity. In the pre-genome era, dead enzymes were thought to occur only rarely. However, they now have been shown to represent upwards of 10% of the total enzyme population in many families. The al...
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| Опубликовано в: : | Expert Opin Drug Metab Toxicol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4937717/ https://ncbi.nlm.nih.gov/pubmed/26558415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425255.2016.1108406 |
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