Significance and Regional Dependency of Peptide Transporter (PEPT) 1 in the Intestinal Permeability of Glycylsarcosine: In Situ Single-Pass Perfusion Studies in Wild-Type and Pept1 Knockout Mice

The purpose of this study was to evaluate the role, relevance, and regional dependence of peptide transporter (PEPT) 1 expression and function in mouse intestines using the model dipeptide glycylsarcosine (GlySar). After isolating specific intestinal segments, in situ single-pass perfusions were per...

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Bibliographische Detailangaben
Hauptverfasser: Jappar, Dilara, Wu, Shu-Pei, Hu, Yongjun, Smith, David E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2010
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957162/
https://ncbi.nlm.nih.gov/pubmed/20660104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.110.034025
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