IL-28B/IFN-λ3 Drives Granzyme B Loading and Significantly Increases CTL Killing Activity in Macaques

Type III/λ interferons (IFNs) were discovered less than a decade ago and are still in the process of being characterized. Although previous studies have focused on the function of IFN-λ3 (also known as interleukin (IL)-28B) in a small animal model, it is unknown whether these functions would transla...

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Autors principals: Morrow, Matthew P, Yan, Jian, Pankhong, Panyupa, Shedlock, Devon J, Lewis, Mark G, Talbott, Kendra, Toporovski, Roberta, Khan, Amir S, Sardesai, Niranjan Y, Weiner, David B
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956930/
https://ncbi.nlm.nih.gov/pubmed/20571540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.118
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