Evaluation of Systemic Follistatin as an Adjuvant to Stimulate Muscle Repair and Improve Motor Function in Pompe Mice

Due to the lack of acid α-glucosidase (GAA) activity, Pompe mice develop glycogen storage pathology and progressive skeletal muscle dysfunction with age. Applying either gene or enzyme therapy to reconstitute GAA levels in older, symptomatic Pompe mice effectively reduces glycogen storage in skeleta...

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Bibliografiske detaljer
Main Authors: Foley, Joseph W, Bercury, Scott D, Finn, Patrick, Cheng, Seng H, Scheule, Ronald K, Ziegler, Robin J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2010
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956929/
https://ncbi.nlm.nih.gov/pubmed/20551907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.110
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