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Robust In Vivo Transduction of Nervous System and Neural Stem Cells by Early Gestational Intra Amniotic Gene Transfer Using Lentiviral Vector

Presently, in vivo methods to efficiently and broadly transduce all major cell types throughout both the central (CNS) and peripheral adult nervous system (PNS) are lacking. In this study, we hypothesized that during early fetal development neural cell populations, including neural stem cells (NSCs)...

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Detalhes bibliográficos
Main Authors: Stitelman, David H, Endo, Masayuki, Bora, Archana, Muvarak, Nidal, Zoltick, Philip W, Flake, Alan W, Brazelton, Timothy R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956924/
https://ncbi.nlm.nih.gov/pubmed/20571539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.125
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