Correction of ADAMTS13 Deficiency by In Utero Gene Transfer of Lentiviral Vector encoding ADAMTS13 Genes

Deficiency of A Disintegrin And Metalloprotease with ThromboSpondin (ADAMTS13) results in thrombotic thrombocytopenic purpura (TTP). Plasma infusion or exchange is the only effective treatment to date. We show in this study that an administration of a self-inactivating lentiviral vector encoding hum...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Niiya, Masami, Endo, Masayuki, Shang, Dezhi, Zoltick, Philip W, Muvarak, Nidal E, Cao, Wenjing, Jin, Sheng-Yu, Skipwith, Christopher G, Motto, David G, Flake, Alan W, Zheng, X Long
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2008
Aiheet:
Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613173/
https://ncbi.nlm.nih.gov/pubmed/18957966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.223
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