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The small heat shock protein HspB2 is a novel anti-apoptotic protein that inhibits apical caspase activation in the extrinsic apoptotic pathway

Members of the conserved small heat shock protein (sHSP) family, such as αB-crystallin and Hsp27, are constitutively expressed in diverse malignancies and have been linked to several hallmark features of cancer including apoptosis resistance. In contrast, the sHSP HspB2/MKBP, which shares an interge...

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Detalhes bibliográficos
Main Authors: Oshita, Shayna E., Chen, Feng, Kwan, Toni, Yehiely, Fruma, Cryns, Vincent L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956912/
https://ncbi.nlm.nih.gov/pubmed/20087649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-010-0735-0
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