PRO2000 vaginal gel for prevention of HIV-1 infection (Microbicides Development Programme 301): a phase 3, randomised, double-blind, parallel-group trial

BACKGROUND: Innovative prevention strategies for HIV-1 transmission are urgently needed. PRO2000 vaginal gel was efficacious against HIV-1 transmission in studies in macaques; we aimed to assess efficacy and safety of 2% and 0·5% PRO2000 gels against vaginal HIV-1 transmission in women in sub-Sahara...

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Autors principals: McCormack, Sheena, Ramjee, Gita, Kamali, Anatoli, Rees, Helen, Crook, Angela M, Gafos, Mitzy, Jentsch, Ute, Pool, Robert, Chisembele, Maureen, Kapiga, Saidi, Mutemwa, Richard, Vallely, Andrew, Palanee, Thesla, Sookrajh, Yuki, Lacey, Charles J, Darbyshire, Janet, Grosskurth, Heiner, Profy, Albert, Nunn, Andrew, Hayes, Richard, Weber, Jonathan
Format: Artigo
Idioma:Inglês
Publicat: Lancet Publishing Group 2010
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956883/
https://ncbi.nlm.nih.gov/pubmed/20851460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(10)61086-0
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