PRO2000 vaginal gel for prevention of HIV-1 infection (Microbicides Development Programme 301): a phase 3, randomised, double-blind, parallel-group trial

BACKGROUND: Innovative prevention strategies for HIV-1 transmission are urgently needed. PRO2000 vaginal gel was efficacious against HIV-1 transmission in studies in macaques; we aimed to assess efficacy and safety of 2% and 0·5% PRO2000 gels against vaginal HIV-1 transmission in women in sub-Sahara...

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Hauptverfasser: McCormack, Sheena, Ramjee, Gita, Kamali, Anatoli, Rees, Helen, Crook, Angela M, Gafos, Mitzy, Jentsch, Ute, Pool, Robert, Chisembele, Maureen, Kapiga, Saidi, Mutemwa, Richard, Vallely, Andrew, Palanee, Thesla, Sookrajh, Yuki, Lacey, Charles J, Darbyshire, Janet, Grosskurth, Heiner, Profy, Albert, Nunn, Andrew, Hayes, Richard, Weber, Jonathan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lancet Publishing Group 2010
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956883/
https://ncbi.nlm.nih.gov/pubmed/20851460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(10)61086-0
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