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Maximum growth and survival of estrogen receptor-alpha positive breast cancer cells requires the Sin3A transcriptional repressor

BACKGROUND: Sin3A is an evolutionarily conserved transcriptional repressor which regulates gene expression as part of the multi-protein Sin3 repressive complex. It functions as a scaffold upon which proteins with enzymatic activity dock, including chromatin modifying histone deacetylases. Although r...

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Autors principals: Ellison-Zelski, Stephanie J, Alarid, Elaine T
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956731/
https://ncbi.nlm.nih.gov/pubmed/20920219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-263
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