von Willebrand factor binding to platelet GpIb initiates signals for platelet activation.

The hypothesis that von Willebrand factor (vWF) binding to platelet membrane glycoprotein Ib (GpIb) initiates intracellular pathways of platelet activation was studied. We measured the biochemical responses of intact human platelets treated with ristocetin plus vWF multimers purified from human cryo...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Kroll, M H, Harris, T S, Moake, J L, Handin, R I, Schafer, A I
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295673/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1939645/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115468
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