von Willebrand factor binding to platelet GpIb initiates signals for platelet activation.

The hypothesis that von Willebrand factor (vWF) binding to platelet membrane glycoprotein Ib (GpIb) initiates intracellular pathways of platelet activation was studied. We measured the biochemical responses of intact human platelets treated with ristocetin plus vWF multimers purified from human cryo...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Kroll, M H, Harris, T S, Moake, J L, Handin, R I, Schafer, A I
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295673/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1939645/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115468
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