von Willebrand factor binding to platelet GpIb initiates signals for platelet activation.

The hypothesis that von Willebrand factor (vWF) binding to platelet membrane glycoprotein Ib (GpIb) initiates intracellular pathways of platelet activation was studied. We measured the biochemical responses of intact human platelets treated with ristocetin plus vWF multimers purified from human cryo...

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Pubblicato in:	J Clin Invest
Autori principali:	Kroll, M H, Harris, T S, Moake, J L, Handin, R I, Schafer, A I
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295673/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1939645/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115468
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