Roles of IKK-β, IRF1, and p65 in the Activation of Chemokine Genes by Interferon-γ

Activation of chemokine genes in response to interferon (IFN)-γ or NF-κB is an important aspect of inflammation. Using the chemokine gene ip-10 in mouse embryonic fibroblast cells as an example, we show that the response to IFN-γ is long lasting but secondary: initial STAT1 activation drives IRF1 sy...

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Detalhes bibliográficos
Main Authors: Shultz, David B., Sandhya Rani, M.R., Fuller, John D., Ransohoff, Richard M., Stark, George R.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956658/
https://ncbi.nlm.nih.gov/pubmed/19929594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2009.0034
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