An inherited bleeding disorder linked to a defective interaction between ADP and its receptor on platelets. Its influence on glycoprotein IIb-IIIa complex function.

Much discussion has concerned the central role of ADP in platelet aggregation. We now describe a patient (M.L.) with an inherited bleeding disorder whose specific feature is that ADP induces a limited and rapidly reversible platelet aggregation even at high doses. Platelet shape change and other hem...

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Detalhes bibliográficos
Main Authors: Nurden, P, Savi, P, Heilmann, E, Bihour, C, Herbert, J M, Maffrand, J P, Nurden, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC295660/
https://ncbi.nlm.nih.gov/pubmed/7706468
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