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Tailored Ligand Acceleration of the Cu-Catalyzed Azide-Alkyne Cycloaddition Reaction: Practical and Mechanistic Implications

Tris(heterocyclemethyl)amines containing mixtures of 1,2,3-triazolyl, 2-benzimidazoyl, and 2-pyridyl components were prepared for ligand acceleration of the copper-catalyzed azide-alkyne cycloaddition reaction. Two classes of ligands were identified: those that give rise to high reaction rates in co...

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Main Authors: Presolski, Stanislav I., Hong, Vu, Cho, So-Hye, Finn, M.G.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956586/
https://ncbi.nlm.nih.gov/pubmed/20863116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja105743g
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